Kokando Pharmaceutical Co., Ltd. was established back in 1980 while Byurakku pills were launched in 1991, which became popular around the world. Byurakku pills are a mild laxative containing pico-sulfate sodium, which is an active ingredient. Picosulfate sodium is activated by intestinal bacteria in the colon and hardly degraded in the stomach and the small intestine. It increases intestinal peristalsis and promotes bowel movements by inhibiting water absorption from the intestine. Bowel movements occur in 6 to 8 hours after taking this medication.

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